Tschantz P, Tuchschmid Y
Service de chirurgie, Hôpital des Cadolles, Neuchâtel.
Swiss Surg. 1995(3):140-7.
250 patients aged 65 and more were operated in a general surgical unit and were studied prospectively on admission. 16 parameters have been studied, trying to determine the factors which might induce a risk of post-operative complications. These complications, minor or major, were found in 25% of the cases (62) of whom 11 (4%) died. As expected, this study shows that with the increase in the importance or the number of unfavorable factors, the complication rate rises. The statistical analysis shows that some factors are of low significance, such as the degree of emergency of the surgical operation or hyperglycemia. Other factors are highly significant for predicting complications: increased dependence, bad mental score, anemia, increased prothrombin time, hyponatremia or the presence of other pathological states than those studied. The importance and the type of the surgical operation, particularly bone traumatology, vascular surgery, thoracic and visceral surgery involve a high rate of post-operative complications. The same is true when malnutrition or hypoalbuminemia are present. Advancing age represents per se an augmentation of these risks, because the elderly patients are not able to meet the increased metabolic demand. This loss of reserve capacity is the most important factor that decreases the elderly patient's ability to tolerate operations. The risk factors mentioned above are particularly important because some pathological states can be corrected, and some other preventive measures can be taken before surgery, as far as one is not dealing with emergency.
250名65岁及以上的患者在普通外科病房接受了手术,并在入院时进行了前瞻性研究。研究了16项参数,试图确定可能导致术后并发症风险的因素。这些并发症,无论是轻微还是严重的,在25%的病例(62例)中被发现,其中11例(4%)死亡。正如预期的那样,这项研究表明,随着不利因素的重要性或数量的增加,并发症发生率会上升。统计分析表明,一些因素意义不大,如手术的紧急程度或高血糖。其他因素对预测并发症具有高度显著性:依赖性增加、精神评分差、贫血、凝血酶原时间延长、低钠血症或存在除所研究的病理状态之外的其他病理状态。手术操作的重要性和类型,特别是骨创伤学、血管外科、胸科和内脏外科,术后并发症发生率较高。当存在营养不良或低白蛋白血症时也是如此。年龄增长本身就意味着这些风险的增加,因为老年患者无法满足增加的代谢需求。这种储备能力的丧失是降低老年患者手术耐受性的最重要因素。上述风险因素尤为重要,因为一些病理状态可以得到纠正,并且在手术前可以采取一些其他预防措施,只要不是急诊情况。