Ren F R, Tanaka H, Fukuda N, Gojobori T
Department of Information Medicine, Medical Research Institute, Tokyo Medical and Dental University Yushima 1-5-45, Bunkyo 113, Japan.
Medinfo. 1995;8 Pt 2:899-903.
Ever since the discovery of a molecular clock (constancy of molecular evolutionary rate), many methods have been developed to estimate the molecular evolutionary phylogenetic trees from the homologous nucleic sequences of different species. In this paper, we deal with this problem from the view point of an inductive inference, and apply Rissanen's minimum description length principle to extract the minimum complexity phylogenetic tree. Five mitochondrial DNA sequences from human, common chimpanzee, pygmy chimpanzee, gorilla, and orangutan are used for investigating the validity of this method. It is found that this method is superior to the traditional method in that it still shows a high degree of accuracy, even near the root of phylogenetic trees.
自从发现分子钟（分子进化速率的恒定性）以来，已经开发出许多方法来从不同物种的同源核酸序列估计分子进化系统发育树。在本文中，我们从归纳推理的角度处理这个问题，并应用里桑宁的最小描述长度原理来提取最小复杂度的系统发育树。使用来自人类、普通黑猩猩、侏儒黑猩猩、大猩猩和猩猩的五个线粒体DNA序列来研究该方法的有效性。结果发现，该方法优于传统方法，因为即使在系统发育树的根部附近，它仍显示出高度的准确性。
