Tajima F
Department of Population Genetics, National Institute of Genetics, Shizuoka, Japan.
Mol Biol Evol. 1992 Jan;9(1):168-81. doi: 10.1093/oxfordjournals.molbev.a040705.
A statistical method is developed for estimating the standard errors of branch lengths in a phylogenetic tree reconstructed without assuming equal rates of nucleotide substitution among different lineages. This method can be easily used for testing whether the length of an interior branch in a reconstructed tree is positive, i.e., whether the topology of the tree is correct. Computer simulations indicate that this method is appropriate for a statistical test. As an example, this method is applied to phylogenetic trees reconstructed for the four hominoid species: human, chimpanzee, gorilla, and orangutan. The results obtained show that the present method provides a powerful statistical test.
开发了一种统计方法，用于估计在不假设不同谱系间核苷酸替代率相等的情况下重建的系统发育树中分支长度的标准误差。该方法可轻松用于检验重建树中内部分支的长度是否为正，即树的拓扑结构是否正确。计算机模拟表明该方法适用于统计检验。作为一个例子，该方法应用于为人类、黑猩猩、大猩猩和猩猩这四种类人猿物种重建的系统发育树。所得结果表明本方法提供了一种强大的统计检验。
