Mont M A, Carbone J J, Fairbank A C
Orthopaedic Department, The Johns Hopkins University School of Medicine, Baltimore, MD 21239, USA.
Clin Orthop Relat Res. 1996 Mar(324):169-78. doi: 10.1097/00003086-199603000-00020.
A complete review of the literature disclosed that there were 42 reports of 2025 hips treated by either core decompression (1206 hips) or nonoperative management (819 hips), excluding electrical stimulation, for osteonecrosis of the femoral head. The peer-reviewed published reports included general surveys, prospective studies, and multicenter studies, but excluded case reports. Satisfactory clinical results were reported in 63.5% of hips in 24 studies of core decompression and in 22.7% of hips in 21 studies of nonoperative management. When looking at only precollapse hips, there were 71% versus 34.5% good results, respectively. Recalculation excluding reports by the 4 centers that do the most core decompressions (and report the best results) showed a clinical success rate for core decompression of 53% versus 22.7% for the nonoperatively treated group. Investigators of multiple studies have reported that nonoperative management leads to extremely poor results. Core decompression has been reported to have a notable effect on the natural history and clinical progression in early stages of osteonecrosis of the femoral head. In view of the limitations of this data, further clarification of this effect only can be obtained by large prospective randomized studies.
对文献进行全面回顾后发现,有42篇关于2025例股骨头坏死患者的报道,这些患者接受了髓芯减压术(1206例)或非手术治疗(819例),其中不包括电刺激治疗。同行评审发表的报告包括综合调查、前瞻性研究和多中心研究,但不包括病例报告。在24项髓芯减压术研究中,63.5%的髋关节取得了满意的临床结果;在21项非手术治疗研究中,22.7%的髋关节取得了满意的临床结果。仅观察塌陷前的髋关节时,分别有71%和34.5%的髋关节取得了良好的结果。排除进行髓芯减压术最多(且报告结果最佳)的4个中心的报告后重新计算发现,髓芯减压术的临床成功率为53%,而非手术治疗组为22.7%。多项研究的研究者报告称,非手术治疗的结果极差。据报道,髓芯减压术对股骨头坏死早期的自然病程和临床进展有显著影响。鉴于这些数据的局限性,只有通过大型前瞻性随机研究才能进一步明确这种影响。