Abu-Shakra M, Lee P
University of Toronto Rheumatic Disease Unit, Wellesley Hospital, Canada.
J Rheumatol. 1995 Nov;22(11):2100-2.
To compare the mortality rate in patients with systemic sclerosis (SSc) with that of the general population.
Standardized mortality ratios (SMR) were calculated for 237 patients with SSc followed prospectively, using age and sex specific mortality rates in Ontario for the period 1976-1990.
The overall SMR for the SSc cohort was 4.69. The mortality rate was greater with diffuse than with limited scleroderma (SMR 6.18 and 3.80, respectively), but not different between men and women.
The mortality rate in SSc is increased compared to that of the general population, especially in the subset with diffuse disease.
比较系统性硬化症（SSc）患者的死亡率与普通人群的死亡率。
对237例前瞻性随访的SSc患者计算标准化死亡率（SMR），采用1976 - 1990年安大略省特定年龄和性别的死亡率。
SSc队列的总体SMR为4.69。弥漫性硬皮病的死亡率高于局限性硬皮病（SMR分别为6.18和3.80），但男女之间无差异。
与普通人群相比，SSc患者的死亡率升高，尤其是在弥漫性疾病亚组中。
