Merola C, Albarracin C, Lebowitz P, Bienkowski R S, Barst S M
Department of Anesthesiology, Schneider Children's Hospital, Long Island Jewish Medical Center, New Hyde Park, New York 11040, USA.
Paediatr Anaesth. 1995;5(6):375-8. doi: 10.1111/j.1460-9592.1995.tb00330.x.
We examined records of sedations provided by the paediatric anaesthesiology staff for 455 children (ages 1 mo-17 yr) undergoing MRI or CT scans at our institution over a twelve-month period with regard to the monitoring of adverse events: excessive sedation, agitation, vomiting, hypoxaemia, and major airway compromise. One hundred-and-thirty-one patients (29%) received chloral hydrate; 324 patients (71%) received propofol. All patients were monitored with continuous noninvasive pulse oximetry and received supplemental oxygen via nasal cannulae. Of the patients who received chloral hydrate, 64 (49%) were over one year of age; of the patients who received propofol, 318 (98%) were one year of age or older. In the chloral hydrate group, 23 patients (19%) were deemed excessively sedated and four patients (3%) were agitated; no patients in the propofol group experienced any of the adverse outcomes reviewed. Furthermore, no patients in either group had significant airway compromise and none was admitted to the hospital as a result of the sedation.
我们检查了儿科麻醉科工作人员为在我们机构进行为期十二个月的磁共振成像（MRI）或计算机断层扫描（CT）的455名儿童（年龄1个月至17岁）提供镇静的记录，以监测不良事件：镇静过度、躁动、呕吐、低氧血症和严重气道阻塞。131名患者（29%）接受了水合氯醛；324名患者（71%）接受了丙泊酚。所有患者均通过连续无创脉搏血氧饱和度监测，并通过鼻导管接受补充氧气。接受水合氯醛的患者中，64名（49%）年龄超过一岁；接受丙泊酚的患者中，318名（98%）年龄为一岁或以上。在水合氯醛组中，23名患者（19%）被认为镇静过度，4名患者（3%）出现躁动；丙泊酚组中没有患者出现任何所审查的不良后果。此外，两组中均没有患者出现严重气道阻塞，也没有患者因镇静而住院。
