Said G
Université Paris-Sud, France.
Baillieres Clin Neurol. 1995 Nov;4(3):489-503.
Vasculitis is a common and treatable cause of neuropathy. In most cases, necrotizing arteritis of the type observed in polyarteritis nodosa is responsible for the lesions, but classification of vasculitis is still uncertain. The neuropathy often occurs in the context of a multisystem disorder, but in a substantial proportion of patients, especially among patients seen by neurologists, the neuropathy is the first and only manifestation of vasculitis. In such cases, the diagnosis can only be reached by performance of a nerve and muscle biopsy. Ischaemic nerve lesions can also result from secondary vasculitis in a number of inflammatory, infectious and immune-mediated disorders of the peripheral nervous system.
血管炎是一种常见且可治疗的神经病变病因。在大多数情况下,结节性多动脉炎中所见类型的坏死性动脉炎是病变的原因,但血管炎的分类仍不明确。神经病变常发生在多系统疾病的背景下,但在相当一部分患者中,尤其是在神经科医生诊治的患者中,神经病变是血管炎的首发且唯一表现。在这种情况下,只有通过进行神经和肌肉活检才能做出诊断。缺血性神经病变也可由周围神经系统的多种炎症、感染和免疫介导性疾病中的继发性血管炎引起。