Buser D, Dula K, Hirt H P, Schenk R K
Department of Oral Surgery, University of Berne, Switzerland.
J Oral Maxillofac Surg. 1996 Apr;54(4):420-32; discussion 432-3. doi: 10.1016/s0278-2391(96)90113-5.
This study evaluated predictability and treatment outcome of the combined application of autografts and expanded-polytetrafluoroethylene (e-PTFE) membranes for lateral ridge augmentation in partially edentulous patients using a staged approach.
Forty partially edentulous patients were consecutively treated. Emphasis was given to a lateral incision technique, perforation of the cortex to open the marrow cavity, stable placement of corticocancellous autografts and bone chips, precise adaptation of the e-PTFE membranes and stabilization with miniscrews, and a tension-free primary soft tissue closure. After 7 to 13 months, the sites were reopened for membrane removal and implant placement.
All but one patient showed complication-free soft tissue healing. After reopening, 38 patients exhibited excellent ridge augmentation, whereas two had compromised results, with soft tissue encapsulation of some bone chips. None of the applied block grafts showed clinical signs of resorption. Preaugmentation and postaugmentation measurements showed an enlargement of the crest width from a mean of 3.5 mm to 7.1 mm. This allowed the placement of nonsubmerged titanium implants in all 40 patients.
The current study demonstrates that the combined application of autografts and e-PTFE membranes is a predictable surgical procedure for lateral ridge augmentation that results in an enlargement of the alveolar crest in partially edentulous patients. The autografts support the membrane and activate bone formation with their osteoconductive and osteoinductive properties. The membrane acts as a physical barrier to nonosteogenic soft tissue cells, and protects the autografts against resorption during healing.
本研究采用分期方法评估自体骨移植与膨体聚四氟乙烯(e-PTFE)膜联合应用于部分牙列缺损患者侧方牙槽嵴增高术的可预测性及治疗效果。
连续治疗40例部分牙列缺损患者。重点关注侧方切口技术、皮质骨穿孔以打开骨髓腔、皮质松质骨自体骨移植块和骨屑的稳定植入、e-PTFE膜的精确贴合及微型螺钉固定,以及无张力的一期软组织关闭。7至13个月后,再次切开术区取出膜并植入种植体。
除1例患者外,所有患者软组织愈合均无并发症。再次切开术后,38例患者牙槽嵴增高效果良好,2例效果欠佳,部分骨屑出现软组织包裹。所有应用的块状移植骨均未出现临床吸收迹象。术前和术后测量显示牙槽嵴宽度从平均3.5mm增加至7.1mm。这使得所有40例患者均能植入非潜入式钛种植体。
本研究表明自体骨移植与e-PTFE膜联合应用是一种可预测的侧方牙槽嵴增高手术方法,可使部分牙列缺损患者的牙槽嵴增大。自体骨移植块支撑膜并通过其骨传导和骨诱导特性激活骨形成。膜作为非成骨软组织细胞的物理屏障,在愈合过程中保护自体骨移植块不被吸收。