Attiyeh F F, Jensen M, Huvos A G, Fracchia A
Surg Gynecol Obstet. 1977 Jun;144(6):839-42.
A retrospective analysis was made of 105 patients with primary operable carcinoma of the breast with positive axillary nodes who had been observed for a 14 year period after radical mastectomy. Patients with micrometastasis alone, especially if only level I is involved, have a good prognosis with 85 and 77 per cent survival rates at ten and 14 years, respectively. No patients had more than three micrometastasis. Patients with four or more positive nodes have a much worse prognosis than do those with three or less positive nodes. Macrometastasis at any level carries a poor prognosis. Since these data show no significant difference between the ten and 14 year survival rates, the ten year survival rate is, therefore, a valid one for long term evaluation of the treatment of carcinoma of the breast.
对105例原发性可手术乳腺癌且腋窝淋巴结阳性患者进行了回顾性分析，这些患者在根治性乳房切除术后接受了14年的观察。仅存在微转移的患者，尤其是仅累及I级的患者，预后良好，10年和14年生存率分别为85%和77%。没有患者的微转移超过3个。有4个或更多阳性淋巴结的患者预后比有3个或更少阳性淋巴结的患者差得多。任何水平的大转移预后都很差。由于这些数据显示10年和14年生存率之间没有显著差异，因此10年生存率对于乳腺癌治疗的长期评估是一个有效的指标。
