Moore L L, Valuck R, McDougall C, Fink W
Payless Drug, Denver, CO, USA.
Contraception. 1995 Oct;52(4):215-9. doi: 10.1016/0010-7824(95)00189-h.
With the recent introduction and growing popularity of Depo-Provera Contraceptive Injection, concern about the potential for weight gain during treatment has been raised. The purpose of the present study was to determine whether or not Depo-Provera Contraceptive Injection is associated with greater weight gain, and incidence thereof, than Norplant implants or oral contraceptives. A retrospective chart review of patients seen at a state- and federally-funded clinic was conducted. Fifty women in each treatment group who met the study criteria were identified and included in the study evaluation. Mean one-year weight gain for subjects in each group was as follows: -2.0 pounds in the oral contraceptive group, -1.8 pounds in the Norplant implants group, and +0.1 pounds in the Depo-Provera Contraceptive Injection group. While results among treatment groups differed slightly, no significant weight change occurred in any of the treatment groups.
随着醋酸甲羟孕酮避孕针剂的近期推出及其日益普及，人们对治疗期间体重增加的可能性产生了担忧。本研究的目的是确定醋酸甲羟孕酮避孕针剂是否比皮下埋植避孕剂或口服避孕药导致更多的体重增加及其发生率。对一家由州政府和联邦政府资助的诊所的患者病历进行了回顾性研究。确定了每个治疗组中符合研究标准的50名女性并纳入研究评估。每组受试者的平均一年体重增加情况如下：口服避孕药组为-2.0磅，皮下埋植避孕剂组为-1.8磅，醋酸甲羟孕酮避孕针剂组为+0.1磅。虽然治疗组之间的结果略有不同，但任何一个治疗组均未出现显著的体重变化。
