嗜甲基甲基杆菌AM1中pqqE和pqqF的特性及核苷酸序列
Characterization and nucleotide sequence of pqqE and pqqF in Methylobacterium extorquens AM1.
作者信息
Springer A L, Ramamoorthi R, Lidstrom M E
机构信息
Environmental Engineering Science, California Institute of Technology, Pasadena 91125, USA.
出版信息
J Bacteriol. 1996 Apr;178(7):2154-7. doi: 10.1128/jb.178.7.2154-2157.1996.
Abstract
Methylobacterium extorquens AM1 pqqEF are genes required for synthesis of pyrroloquinoline quinone (PQQ). The nucleotide sequence of these genes indicates PqqE belongs to an endopeptidase family, including PqqF of Klebsiella pneumoniae, and M. extorquens AM1 PqqF has low identity with the same endopeptidase family. M. extorquens AM1 pqqE complemented a K. pneumoniae pqqF mutant.
摘要
嗜甲基菌AM1的pqqEF基因是合成吡咯喹啉醌（PQQ）所必需的基因。这些基因的核苷酸序列表明PqqE属于一个内肽酶家族，包括肺炎克雷伯菌的PqqF，且嗜甲基菌AM1的PqqF与同一内肽酶家族的同源性较低。嗜甲基菌AM1的pqqE可互补肺炎克雷伯菌的pqqF突变体。
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