Hoffenberg E F, Kozlowski P, Salerno T A, Deslauriers R
Institute for Biodiagnostics, National Research Council Canada, Winnipeg, Manitoba, Canada.
J Surg Res. 1996 Apr;62(1):135-43. doi: 10.1006/jsre.1996.0186.
31P magnetic resonance spectroscopy (MRS) has been used for several decades as an analytical tool in cardiac research and is quickly emerging as a diagnostic tool, due to its ability to continuously and noninvasively monitor levels of high energy phosphates, inorganic phosphate, and intracellular pH in localized regions of the myocardium. This article provides a brief review of basic MRS principles, presents some current techniques of localized spectroscopy related to experimental and clinical cardiac research, and discusses their advantages and disadvantages.
31P磁共振波谱(MRS)在心脏研究中作为一种分析工具已使用了数十年,并且由于其能够连续、无创地监测心肌局部区域的高能磷酸盐、无机磷酸盐和细胞内pH水平,正迅速成为一种诊断工具。本文简要回顾了MRS的基本原理,介绍了一些与实验性和临床心脏研究相关的局部波谱分析的当前技术,并讨论了它们的优缺点。