Schroeder J S, Lamb I H, Harrison D C
Am J Cardiol. 1977 May 26;39(6):829-32. doi: 10.1016/s0002-9149(77)80035-0.
Approximately 300 persons a year who are admitted to the Stanford University Hospital coronary care unit because of prolong ischemic chest pain and transient S-T changes do not manifest evidence of a myocardial infarction during their hospital stay. In a retrospective study carried out in 170 such patients, follow-up data obtained during a mean of 17.9 months revealed rates of mortality from cardiovascular causes of 4.2 percent for 1 month, 10.1 percent for 1 year and 19.7 percent for the entire follow-up period. Ten (40 percent) of the 23 deaths that occurred were sudden and 13 were due to acute myocardial infarction or its complications. Another 21 patients had a nonfatal myocardial infarction during this follow-up period. The data confirm the impression that patients with suspected myocardial infarction who do not have an infarction in the coronary care unit are at high risk for cardiovascular deaths after hospital discharge. Efforts are under way to define further a high risk subgroup on the basis of clinical indications before discharge.
每年约有300人因持续性缺血性胸痛和短暂性S-T段改变入住斯坦福大学医院冠心病监护病房,但在住院期间未表现出心肌梗死的证据。在对170例此类患者进行的一项回顾性研究中,平均17.9个月的随访数据显示,心血管原因导致的死亡率在1个月时为4.2%,1年时为10.1%,整个随访期为19.7%。发生的23例死亡中,10例(40%)为猝死,13例死于急性心肌梗死或其并发症。另外21例患者在此随访期间发生了非致命性心肌梗死。这些数据证实了这样一种印象,即在冠心病监护病房未发生心肌梗死的疑似心肌梗死患者出院后心血管死亡风险很高。目前正在努力根据出院前的临床指征进一步确定高风险亚组。