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因胸痛入住冠心病监护病房的患者:后续心血管死亡的高危亚组。

Patients admitted to the coronary care unit for chest pain: high risk subgroup for subsequent cardiovascular death.

作者信息

Schroeder J S, Lamb I H, Harrison D C

出版信息

Am J Cardiol. 1977 May 26;39(6):829-32. doi: 10.1016/s0002-9149(77)80035-0.

DOI:10.1016/s0002-9149(77)80035-0
PMID:860694
Abstract

Approximately 300 persons a year who are admitted to the Stanford University Hospital coronary care unit because of prolong ischemic chest pain and transient S-T changes do not manifest evidence of a myocardial infarction during their hospital stay. In a retrospective study carried out in 170 such patients, follow-up data obtained during a mean of 17.9 months revealed rates of mortality from cardiovascular causes of 4.2 percent for 1 month, 10.1 percent for 1 year and 19.7 percent for the entire follow-up period. Ten (40 percent) of the 23 deaths that occurred were sudden and 13 were due to acute myocardial infarction or its complications. Another 21 patients had a nonfatal myocardial infarction during this follow-up period. The data confirm the impression that patients with suspected myocardial infarction who do not have an infarction in the coronary care unit are at high risk for cardiovascular deaths after hospital discharge. Efforts are under way to define further a high risk subgroup on the basis of clinical indications before discharge.

摘要

每年约有300人因持续性缺血性胸痛和短暂性S-T段改变入住斯坦福大学医院冠心病监护病房,但在住院期间未表现出心肌梗死的证据。在对170例此类患者进行的一项回顾性研究中,平均17.9个月的随访数据显示,心血管原因导致的死亡率在1个月时为4.2%,1年时为10.1%,整个随访期为19.7%。发生的23例死亡中,10例(40%)为猝死,13例死于急性心肌梗死或其并发症。另外21例患者在此随访期间发生了非致命性心肌梗死。这些数据证实了这样一种印象,即在冠心病监护病房未发生心肌梗死的疑似心肌梗死患者出院后心血管死亡风险很高。目前正在努力根据出院前的临床指征进一步确定高风险亚组。

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Am J Cardiol. 1977 May 26;39(6):829-32. doi: 10.1016/s0002-9149(77)80035-0.
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引用本文的文献

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Evaluating a new graphical ordinal logit method (GOLDminer) in the diagnosis of myocardial infarction utilizing clinical features and laboratory data.利用临床特征和实验室数据,评估一种用于诊断心肌梗死的新型图形有序logit方法(GOLDminer)。
Yale J Biol Med. 1999 Jul-Aug;72(4):259-68.
3
Diagnosis of slight and subacute coronary attacks in the community.社区中轻度和亚急性冠状动脉发作的诊断。
Br Heart J. 1981 Mar;45(3):299-310. doi: 10.1136/hrt.45.3.299.
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Prognosis of patients with "chest pain ?cause".“胸痛 - 病因不明”患者的预后
Br Med J (Clin Res Ed). 1981 Feb 7;282(6262):431-3. doi: 10.1136/bmj.282.6262.431.
5
Additional molsidomine in refractory unstable angina pectoris.难治性不稳定型心绞痛中额外使用莫西赛利。
Cardiovasc Drugs Ther. 1988 May;2(1):107-11. doi: 10.1007/BF00054260.
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Aspirin for unstable angina?阿司匹林用于不稳定型心绞痛?
Br Med J (Clin Res Ed). 1986 Jul 5;293(6538):1-2. doi: 10.1136/bmj.293.6538.1.
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Six year follow up of a consecutive series of patients presenting to the coronary care unit with acute chest pain: prognostic importance of the electrocardiogram.对连续收治至冠心病监护病房的急性胸痛患者进行的六年随访:心电图的预后重要性
Br Heart J. 1990 May;63(5):267-72. doi: 10.1136/hrt.63.5.267.
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