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美国白人中年龄和紫外线对皮肤癌发病率影响的数学模型。

Mathematical models of age and ultraviolet effects on the incidence of skin cancer among whites in the United States.

作者信息

Fears T R, Scotto J, Schneiderman M A

出版信息

Am J Epidemiol. 1977 May;105(5):420-7. doi: 10.1093/oxfordjournals.aje.a112400.

Abstract

That sunlight leads to skin cancer has been generally accepted for nearly a century. Physical data are, for the first time, available which support this hypothesis. The authors have found that a simple power relationship can be used to describe the data and that the form of this power function suggests that the risk of nonmelanoma skin cancer is related to cumulative lifetime ultraviolet (UV) exposure and that the risk of melanoma skin cancer is related to annual UV exposure. The authors emphasize that skin cancer risk also depends on location-specific demographic variables other than ultraviolet radiation.

摘要

近一个世纪以来,阳光会导致皮肤癌这一观点已被普遍接受。首次有物理数据支持这一假说。作者发现,可用一种简单的幂函数关系来描述这些数据,且这种幂函数的形式表明,非黑色素瘤皮肤癌的风险与一生中累积的紫外线(UV)暴露有关,而黑色素瘤皮肤癌的风险与年度紫外线暴露有关。作者强调,皮肤癌风险还取决于紫外线辐射以外的特定地理位置的人口统计学变量。

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