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绝经伴或不伴系统性高血压的眼压升高效应

Ocular hypertensive effect of menopause with and without systemic hypertension.

作者信息

Qureshi I A

机构信息

Department of Physiology, Basic Medical Sciences Institute, Jinnah Postgraduate Medical Centre, Karachi, Pakistan.

出版信息

Acta Obstet Gynecol Scand. 1996 Mar;75(3):266-9. doi: 10.3109/00016349609047099.

DOI:10.3109/00016349609047099
PMID:8607341
Abstract

BACKGROUND

Mean intraocular pressure in postmenopausal women is higher than that in menstruating women. Intraocular pressure is positively correlated with systemic blood pressure. No previous study has compared intraocular pressure in postmenopausal women with systemic hypertension and those without.

PURPOSE

To investigate the effects of menopause on intraocular pressure in subjects with and without high blood pressure, after eliminating those factors that can affect intraocular pressure.

METHODS

Normotensive menstruating and menopausal, along with hypertensive menopausal subjects of the same age groups were studied. Intraocular pressure was measured with the Goldmann applanation tonometer.

RESULTS

The mean intraocular pressure of the normotensive and hypertensive postmenopausal women were 0.73+/-0.27 (p<0.05), and 1.09+/-0.34 (p<0.01) mmHg higher than normotensive menstruating women respectively. The mean intraocular pressure of hypertensive postmenopausal women was 0.36+/-0.15 mmHg (p<0.05) higher than that of normotensive postmenopausal women.

CONCLUSIONS

Menopause significantly increases intraocular pressure. Mean intraocular pressure of hypertensive postmenopausal women was significantly (p<0.05) higher than that of normotensive postmenopausal women. Knowledge of the normal level of intraocular pressure during various stages of female sexual life may help glaucoma screeners.

摘要

背景

绝经后女性的平均眼压高于处于月经期的女性。眼压与全身血压呈正相关。此前尚无研究比较绝经后患有和未患有系统性高血压女性的眼压情况。

目的

在排除可能影响眼压的因素后,研究绝经对患有和未患有高血压的受试者眼压的影响。

方法

对年龄相同的血压正常的处于月经期和绝经后的女性,以及患有高血压的绝经后女性进行研究。使用Goldmann压平眼压计测量眼压。

结果

血压正常的绝经后女性和患有高血压的绝经后女性的平均眼压分别比血压正常的处于月经期的女性高0.73±0.27(p<0.05)和1.09±0.34(p<0.01)mmHg。患有高血压的绝经后女性的平均眼压比血压正常的绝经后女性高0.36±0.15 mmHg(p<0.05)。

结论

绝经会显著升高眼压。患有高血压的绝经后女性的平均眼压显著高于(p<0.05)血压正常的绝经后女性。了解女性不同性生活阶段眼压的正常水平可能有助于青光眼筛查人员。

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