De Queiroz A A, Gallardo A, Román J S, Higa O Z
Escola Federal de Engenharia de Itajubá, Departamento de Ciências (ICI), Brazil.
J Biomater Sci Polym Ed. 1995;7(6):523-30. doi: 10.1163/156856295x00580.
Copolymerization of N,N-dimethylacrylamide (DMAA) and p-acryloyloxiacetanilide (AOA) was carried out at different mole ratios of the monomers to obtain copolymers of varying compositions. DMAA contents were very near to the corresponding monomer feed and varied between 0.20 and 0.80. Investigation of the protein adsorption of these polymer surfaces showed that copolymers with higher DMAA content adsorbed more albumin than fibrinogen. The scanning electron micrographs of the polymer-coated coverslips after contact with blood showed an antithrombogenic behaviour of these surfaces.
以不同的单体摩尔比进行N，N-二甲基丙烯酰胺（DMAA）和对丙烯酰氧基乙酰苯胺（AOA）的共聚反应，以获得不同组成的共聚物。DMAA含量非常接近相应的单体进料，在0.20至0.80之间变化。对这些聚合物表面的蛋白质吸附研究表明，DMAA含量较高的共聚物比纤维蛋白原吸附更多的白蛋白。与血液接触后聚合物涂层盖玻片的扫描电子显微镜照片显示了这些表面的抗血栓形成行为。
