Cookson B
Laboratory of Hospital Infection, Central Public Health Laboratory, London, UK.
J Chemother. 1995 Jul;7 Suppl 3:93-8.
The prevalence of methicillin-resistant Staphylococcus aureus (MRSA) varies in different European countries, in different cities in the same country or even within a city or a hospital. It is thought that the overall incidence of MRSA is higher than ever before, although the reasons for this are unclear. MRSA typing can identify epidemic MRSA in many countries. The spread of a closely related clone is Northern Europe is a cause for concern, as it is resistant to many agents. In the UK, control measures are threatened by changing patterns of health care and patient demography. Resistance to mupirocin, a valuable agent in the control of MRSA, has emerged in many hospitals in the UK, thus the agent must be used judiciously.
耐甲氧西林金黄色葡萄球菌(MRSA)在欧洲不同国家、同一国家的不同城市甚至在一个城市或一家医院内部的流行情况各不相同。据认为,MRSA的总体发病率比以往任何时候都高,尽管其原因尚不清楚。在许多国家,MRSA分型可以识别流行的MRSA。在北欧,一个密切相关的克隆菌株的传播令人担忧,因为它对许多药物具有耐药性。在英国,医疗保健模式和患者人口结构的变化对控制措施构成了威胁。在英国的许多医院中,已经出现了对莫匹罗星(一种控制MRSA的重要药物)的耐药性,因此必须谨慎使用该药物。