霍乱毒素B亚基作为跨粘膜载体递送和免疫调节系统用于诱导抗感染和抗病理免疫。 - Suppr

Suppr

超能文献

Cholera toxin B subunit as transmucosal carrier-delivery and immunomodulating system for induction of antiinfectious and antipathological immunity.

作者信息

Czerkinsky C, Sun J B, Lebens M, Li B L, Rask C, Lindblad M, Holmgren J

机构信息

Department of Medical Microbiology and Immunology, University of Göteborg, Sweden.

出版信息

Ann N Y Acad Sci. 1996 Feb 13;778:185-93. doi: 10.1111/j.1749-6632.1996.tb21127.x.

DOI:10.1111/j.1749-6632.1996.tb21127.x

PMID:8610972

Abstract

摘要

相似文献

Cholera toxin B subunit as transmucosal carrier-delivery and immunomodulating system for induction of antiinfectious and antipathological immunity.霍乱毒素B亚基作为跨粘膜载体递送和免疫调节系统用于诱导抗感染和抗病理免疫。

Ann N Y Acad Sci. 1996 Feb 13;778:185-93. doi: 10.1111/j.1749-6632.1996.tb21127.x.

Dermal enhancement: bacterial products on intact skin induce and augment organ-specific autoimmune disease.皮肤增强：完整皮肤上的细菌产物会诱发并加剧器官特异性自身免疫性疾病。

J Immunol. 2004 Jan 1;172(1):302-9. doi: 10.4049/jimmunol.172.1.302.

Active immunity or tolerance to foods in patients with celiac disease or inflammatory bowel disease.乳糜泻或炎症性肠病患者对食物的主动免疫或耐受性。

Ann N Y Acad Sci. 1996 Feb 13;778:202-16. doi: 10.1111/j.1749-6632.1996.tb21129.x.

Protection from insulin dependent diabetes mellitus afforded by insulin antigens in incomplete Freund's adjuvant depends on route of administration.胰岛素抗原在不完全弗氏佐剂中对胰岛素依赖型糖尿病的保护作用取决于给药途径。

J Autoimmun. 1998 Apr;11(2):127-30. doi: 10.1006/jaut.1997.0184.

Cholera toxin B subunit: an efficient transmucosal carrier-delivery system for induction of peripheral immunological tolerance.霍乱毒素B亚基：一种用于诱导外周免疫耐受的高效跨黏膜载体递送系统。

Proc Natl Acad Sci U S A. 1994 Nov 8;91(23):10795-9. doi: 10.1073/pnas.91.23.10795.

Oral administration of cholera toxin B-insulin conjugates protects NOD mice from autoimmune diabetes by inducing CD4+ regulatory T-cells.口服霍乱毒素B-胰岛素偶联物可通过诱导CD4 +调节性T细胞保护非肥胖糖尿病（NOD）小鼠免受自身免疫性糖尿病的侵害。

Diabetes. 1999 Nov;48(11):2150-6. doi: 10.2337/diabetes.48.11.2150.

Plant-based vaccines for oral delivery of type 1 diabetes-related autoantigens: Evaluating oral tolerance mechanisms and disease prevention in NOD mice.植物源疫苗经口服递呈 1 型糖尿病相关自身抗原：在 NOD 小鼠中评估口服耐受机制和疾病预防。

Sci Rep. 2017 Feb 13;7:42372. doi: 10.1038/srep42372.

Suppression of diabetes in non-obese diabetic (NOD) mice by oral administration of a cholera toxin B subunit-insulin B chain fusion protein vaccine produced in silkworm.通过口服家蚕生产的霍乱毒素B亚基-胰岛素B链融合蛋白疫苗抑制非肥胖糖尿病（NOD）小鼠的糖尿病。

Vaccine. 2007 Feb 9;25(8):1444-51. doi: 10.1016/j.vaccine.2006.10.039. Epub 2006 Nov 3.

Nasal administration of CTB-insulin induces active tolerance against autoimmune diabetes in non-obese diabetic (NOD) mice.在非肥胖糖尿病（NOD）小鼠中，经鼻给予霍乱毒素B亚单位-胰岛素可诱导对自身免疫性糖尿病的主动耐受。

Clin Exp Immunol. 2002 Nov;130(2):204-11. doi: 10.1046/j.1365-2249.2002.01988.x.

Treatment of experimental autoimmune encephalomyelitis by feeding myelin basic protein conjugated to cholera toxin B subunit.通过喂食与霍乱毒素B亚基偶联的髓鞘碱性蛋白治疗实验性自身免疫性脑脊髓炎。

Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):7196-201. doi: 10.1073/pnas.93.14.7196.

引用本文的文献

Cellular Activity of Typhimurium ArtAB Toxin and Its Receptor-Binding Subunit.鼠伤寒沙门氏菌 ArtAB 毒素及其受体结合亚单位的细胞活性。

Toxins (Basel). 2021 Aug 27;13(9):599. doi: 10.3390/toxins13090599.

Oral delivery of therapeutic proteins bioencapsulated in plant cells: preclinical and clinical advances.植物细胞生物包封的治疗性蛋白质的口服给药：临床前和临床进展

Curr Opin Colloid Interface Sci. 2021 Aug;54. doi: 10.1016/j.cocis.2021.101452. Epub 2021 Mar 24.

Cholera toxin B: one subunit with many pharmaceutical applications.霍乱毒素B：具有多种药物应用的一个亚基。

Toxins (Basel). 2015 Mar 20;7(3):974-96. doi: 10.3390/toxins7030974.

AB toxins: a paradigm switch from deadly to desirable.AB 毒素：从致命到理想的范式转变。

Toxins (Basel). 2010 Jul;2(7):1612-45. doi: 10.3390/toxins2071612. Epub 2010 Jun 25.

Coupling of oral human or porcine insulin to the B subunit of cholera toxin (CTB) overcomes critical antigenic differences for prevention of type I diabetes.将人源或猪源口服胰岛素与霍乱毒素（CTB）的B亚基偶联，可克服关键的抗原差异，从而预防I型糖尿病。

Clin Exp Immunol. 2003 Oct;134(1):38-45. doi: 10.1046/j.1365-2249.2003.02255.x.

Schwann cells are removed from the spinal cord after effecting recovery from paraplegia.在截瘫恢复后，施万细胞从脊髓中被移除。

J Neurosci. 2000 Dec 15;20(24):9215-23. doi: 10.1523/JNEUROSCI.20-24-09215.2000.

Antigen uptake and trafficking in human intestinal epithelial cells.抗原在人肠道上皮细胞中的摄取与转运。

Dig Dis Sci. 2000 Jul;45(7):1451-61. doi: 10.1023/a:1005536927137.

Mucosal immunity and tolerance: relevance to vaccine development.黏膜免疫与耐受性：与疫苗研发的相关性。

Immunol Rev. 1999 Aug;170(1):197-222. doi: 10.1111/j.1600-065x.1999.tb01339.x.

Effectiveness of liposomes possessing surface-linked recombinant B subunit of cholera toxin as an oral antigen delivery system.具有表面连接霍乱毒素重组B亚基的脂质体作为口服抗原递送系统的有效性。

Infect Immun. 1998 Sep;66(9):4299-304. doi: 10.1128/IAI.66.9.4299-4304.1998.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验