Beinert H, Kiley P
Institute for Enzyme Research, College of Agriculture and Life Sciences, University of Wisconsin, Madison 53706, USA.
FEBS Lett. 1996 Mar 11;382(1-2):218-9; discussion 220-1. doi: 10.1016/0014-5793(96)00140-8.
Attention is drawn to a mechanism of redox control of gene expression involving Fe-S proteins which depends on the disassembly and reassembly of Fe-S clusters rather than a change in oxidation state. Iron Regulatory Protein (IRP)/aconitase and FNR are discussed as examples for such a mechanism.
请注意一种涉及铁硫蛋白的基因表达氧化还原控制机制,该机制依赖于铁硫簇的拆卸和重新组装,而非氧化态的变化。以铁调节蛋白(IRP)/乌头酸酶和FNR为例对这种机制进行了讨论。