Aejmelaeus R, Metsä-Ketelä T, Laippala P, Alho H
Department of Pharmacology, Clinical Pharmacology and Toxicology, Medical School, University of Tampere, Finland.
FEBS Lett. 1996 Apr 15;384(2):128-30. doi: 10.1016/0014-5793(96)00296-7.
The total peroxyl radical scavenging capacity (TRAP) of human plasma was measured from pneumonia patients and controls. TRAP and its main components, ascorbic acid, alpha-tocopherol, uric acid or protein thiol groups, were unaltered, but the concentration of unidentified antioxidants in pneumonia patients was significantly reduced. Our results indicate that human plasma may contain so far unidentified antioxidants depleted in infection.
