Aejmelaeus R, Ketelä T M, Pirttilä T, Hervonen A, Alho H
Laboratory of Neurobiology, Medical School, University of Tampere, Finland.
Free Radic Res. 1997 Apr;26(4):335-41. doi: 10.3109/10715769709097813.
Plasma total peroxyl radical scavenging capacity was studied in terminal patients who were chronically immobilized because of an acute (stroke) or chronic neurodegenerative disease (Alzheimer's disease). A luminometric assay was used to measure total antioxidant capacity (TRAP). The immobilized patients showed significant decrease in TRAP primarily because of a decrease in the concentration of unknown antioxidants. Our results suggest that human plasma may contain unknown antioxidants, the regulation of which could be related to the basic metabolic rate.
对因急性(中风)或慢性神经退行性疾病(阿尔茨海默病)而长期卧床的晚期患者的血浆总过氧自由基清除能力进行了研究。采用发光分析法测量总抗氧化能力(TRAP)。卧床患者的TRAP显著降低,主要原因是未知抗氧化剂浓度降低。我们的结果表明,人体血浆可能含有未知抗氧化剂,其调节可能与基础代谢率有关。