Johnson R P, Cray W C, Johnson S T
Health of Animals Laboratory, Agriculture and Agri-Food Canada, Guelph, Ontario, Canada.
Infect Immun. 1996 May;64(5):1879-83. doi: 10.1128/iai.64.5.1879-1883.1996.
Oral inoculation of calves and steers with 10(10) CFU of Escherichia coli O157:H7 induced prompt and sustained increases in serum antibodies to O157 lipopolysaccharide. Neutralizing antibodies to verotoxin 1 also increased rapidly in most steers but more gradually in calves. None of the animals developed neutralizing antibodies to verotoxin 2. These serological responses were not correlated with elimination of infection in calves or steers or protection of calves against reinfection with the same strain.
用10(10) 个大肠杆菌O157:H7 菌落形成单位对犊牛和阉牛进行口服接种，可使血清中针对O157脂多糖的抗体迅速且持续增加。大多数阉牛中针对志贺毒素1的中和抗体也迅速增加，但犊牛中增加得较为缓慢。没有动物产生针对志贺毒素2的中和抗体。这些血清学反应与犊牛或阉牛感染的消除或犊牛免受同一菌株再次感染的保护无关。
