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切尔诺贝利地区啮齿动物的高度基因变化。

High levels of genetic change in rodents of Chernobyl.

作者信息

Baker R J, Van Den Bussche R A, Wright A J, Wiggins L E, Hamilton M J, Reat E P, Smith M H, Lomakin M D, Chesser R K

机构信息

Department of Biological Sciences, Texas Tech University, Lubbock, 79409, USA.

出版信息

Nature. 1996 Apr 25;380(6576):707-8. doi: 10.1038/380707a0.

DOI:10.1038/380707a0
PMID:8614463
Abstract

Base-pair substitution rates for the mitochondrial cytochrome beta gene of free-living, native populations of voles collected next to reactor 4 at Chernobyl, Ukraine, were estimated by two independent methods to be in excess of 10(-4) nucleotides per site per generation. These estimates are hundreds of times greater than those typically found in mitochondria of vertebrates, suggesting that the environment resulting from this nuclear power plant disaster is having a measurable genetic impact on the organisms of that region. Despite these DNA changes, vole populations thrive and reproduce in the radioactive regions around the Chernobyl reactor.

摘要

通过两种独立方法估计,乌克兰切尔诺贝利4号反应堆旁采集的野生本地田鼠种群线粒体细胞色素β基因的碱基对替换率超过每代每个位点10^(-4)个核苷酸。这些估计值比脊椎动物线粒体中通常发现的替换率高数百倍,这表明这场核电站灾难所造成的环境正在对该地区的生物产生可测量的遗传影响。尽管存在这些DNA变化,田鼠种群仍在切尔诺贝利反应堆周围的放射性区域繁衍生息。

相似文献

1
High levels of genetic change in rodents of Chernobyl.切尔诺贝利地区啮齿动物的高度基因变化。
Nature. 1996 Apr 25;380(6576):707-8. doi: 10.1038/380707a0.
2
Life in the hot zone around Chernobyl.切尔诺贝利周围热区的生活。
Nature. 1996 Apr 25;380(6576):665-6. doi: 10.1038/380665a0.
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Nucleotide variation in the p53 tumor-suppressor gene of voles from Chernobyl, Ukraine.乌克兰切尔诺贝利田鼠p53肿瘤抑制基因的核苷酸变异
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Variation in mitochondrial DNA control region haplotypes in populations of the bank vole, Clethrionomys glareolus, living in the Chernobyl environment, Ukraine.生活在乌克兰切尔诺贝利环境中的小林姬鼠(Clethrionomys glareolus)种群线粒体DNA控制区单倍型的变异。
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Transgenic plants are sensitive bioindicators of nuclear pollution caused by the Chernobyl accident.转基因植物是切尔诺贝利事故所造成核污染的敏感生物指示物。
Nat Biotechnol. 1998 Nov;16(11):1054-9. doi: 10.1038/3505.
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Fitness loss and germline mutations in barn swallows breeding in Chernobyl.在切尔诺贝利繁殖的家燕的健康衰退与生殖系突变
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[Genetic sequelae of the accident at the Chernobyl nuclear power plant in house mice (Mus musculus)].[家鼠(小家鼠)切尔诺贝利核电站事故的遗传后遗症]
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[Biological effects in natural populations of small rodents in radiation-polluted territories. Dynamics of chromosome aberration frequency in a number of generations of European bank vole (Clethrionomys glareolus, Schreber)].[辐射污染地区小型啮齿动物自然种群中的生物学效应。欧洲林姬鼠(Clethrionomys glareolus, Schreber)若干代染色体畸变频率的动态变化]
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[Species specificity of karyotype instability under conditions of radionuclide contamination (the Chernobyl Nuclear Power Plant) in the voles, Micrototus oeconomus, Micrototus arvalis, and Clethrionomys glareolus].[放射性核素污染(切尔诺贝利核电站)条件下田鼠(Economus田鼠、普通田鼠和棕背䶄)染色体组型不稳定性的物种特异性]
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[The genetic monitoring of the house mouse population from areas contaminated by radionuclides as a result of the accident at the Chernobyl Atomic Electric Power Station].[对因切尔诺贝利核电站事故而受放射性核素污染地区家鼠种群的遗传监测]
Tsitol Genet. 1996 Jul-Aug;30(4):42-8.

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