Lange P H, McIntire K R, Waldmann T A, Hakala T R, Fraley E E
J Urol. 1977 Oct;118(4):593-6. doi: 10.1016/s0022-5347(17)58115-x.
Alpha-fetoprotein and human chorionic gonadotropin levels were measured by radioimmunoassays in 260 patients with genitourinary diseases, including 93 patients with testicular tumors. Elevations of alpha-fetoprotein and human chorionic gonadotropin were associated only with non-seminomatous germ cell testicular tumors. Our 32-month experience with serial measurements of the 2 markers in patients with these tumors shows that alpha-fetoprotein and human chorionic gonadotropin must be determined and that together they serve as accurate and sensitive indicators of metastases and are helpful in determining the effectiveness of therapy. However, they have limited value in the differential diagnosis of scrotal masses.
采用放射免疫分析法对260例泌尿生殖系统疾病患者（包括93例睾丸肿瘤患者）检测了甲胎蛋白和人绒毛膜促性腺激素水平。甲胎蛋白和人绒毛膜促性腺激素升高仅与非精原细胞性生殖细胞睾丸肿瘤相关。我们对这些肿瘤患者连续32个月检测这两种标志物的经验表明，必须测定甲胎蛋白和人绒毛膜促性腺激素，它们共同作为转移的准确而敏感的指标，有助于判定治疗效果。然而，它们在阴囊肿块的鉴别诊断中价值有限。
