Rosen D S, al Sharif Z, Bashir M, al Shabooti A, Pizzarello L D
Helen Keller International, New York, USA.
Eur J Clin Nutr. 1996 Jan;50(1):54-7.
To determine the prevalence of xerophthalmia and the extent of vitamin A deficiency in western Yemen.
A stratified cluster sample of children aged 1-5 years with clinical examination for signs of xerophthalmia as well as blood serum survey.
The 18 districts of western Yemen, of which 10 clusters were chosen at random.
All children aged 1-5 years resident in the cluster sites (n = 2438).
Clinical signs of xerophthalmia, a history of night blindness, serum retinol levels in a random sample of clinically normal children (n =338) in addition to all children with xerophthalmia.
Night blindness was found in 0.5% of the children, Bitot's spots in 1.7%, corneal ulceration in 0.04% and corneal scars in 0.04% Of the subsample, 7.2% (95% confidence interval [c.i.] 4.4-10.0%) had serum retinol values below 10 micrograms/dl; 63.0% (95% c.i. 57.6- 68.4%) had values below 20 micrograms/dl.
Xerophthalmia and vitamin A deficiency are public health problems in western Yemen.
确定也门西部干眼症的患病率以及维生素A缺乏的程度。
对1 - 5岁儿童进行分层整群抽样，进行干眼症体征的临床检查以及血清调查。
也门西部的18个区，随机选取其中10个群组。
居住在群组地点的所有1 - 5岁儿童（n = 2438）。
干眼症的临床体征、夜盲病史、随机抽取的临床正常儿童样本（n = 338）以及所有干眼症儿童的血清视黄醇水平。
0.5%的儿童患有夜盲症，1.7%的儿童有毕脱斑，0.04%的儿童有角膜溃疡，0.04%的儿童有角膜瘢痕。在子样本中，7.2%（95%置信区间[c.i.] 4.4 - 10.0%）的血清视黄醇值低于10微克/分升；63.0%（95% c.i. 57.6 - 68.4%）的值低于20微克/分升。
干眼症和维生素A缺乏是也门西部的公共卫生问题。
