Adair J C, Williamson D J, Schwartz R L, Heilman K M
Department of Neurology, University of Florida College of Medicine, Gainesville, FL 32610-0236, USA.
Neurology. 1996 Mar;46(3):842-3.
A patient developed acute behavioral changes implicating frontal-executive dysfunction. His clinical signs suggested mesencephalic injury, and a cranial MRI scan showed an abnormality restricted to a small region of the ventral midbrain. We suggest that the patient's behavioral disorder originated from disruption of the ventral tegmental area or it projections, structures that influence frontal brain processes via the mesocortical dopamine tract.
一名患者出现急性行为改变，提示额叶执行功能障碍。他的临床体征提示中脑损伤，头颅磁共振成像扫描显示异常局限于腹侧中脑的一个小区域。我们认为，患者的行为障碍源于腹侧被盖区或其投射受损，这些结构通过中脑皮质多巴胺通路影响额叶脑区的活动。
