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开普半岛南非城市黑人人口的血脂和脂蛋白概况——BRISK研究

The lipid and lipoprotein profile of the urban black South Africa population of the Cape Peninsula - the BRISK study.

作者信息

Oelofse A, Jooste P L, Steyn K, Badenhorst C J, Lombard C, Bourne L, Fourie J

机构信息

National Research Programme for Nutritional Intervention, Division for Chronic Diseases of Lifestyle, Tygerberg, W. Cape.

出版信息

S Afr Med J. 1996 Feb;86(2):162-6.

PMID:8619144
Abstract

OBJECTIVE

To determine the lipid and lipoprotein profile of the urban black South African population of the Cape Peninsula.

DESIGN

Cross-sectional design.

SETTING

The seven black residential areas of the Cape Peninsula.

PARTICIPANTS

A stratified proportional sample was drawn from the study area. The sample consisted of 422 men and 544 women aged between 15 and 64 years.

OUTCOME MEASURES

Lipid and lipoprotein levels. Risk levels for coronary heart disease (CHD).

RESULTS

The total cholesterol (TC level) was low compared with other South African groups studied. Men had a mean TC of 3.98 mmol/l and women 4.15 mmol/l. Low-density lipoprotein cholesterol (LDLC) values for men (2.03 mmol/l) were lower than those for women (2.30 mmol/l). Men (1.35 mmol/l) and women (1.37 mmol/l) had similar high-density lipoprotein cholesterol (HDLC) levels. Both sexes had a prevalence of protective HDL/TC ratios above 30% for all age groups. High HDL3C levels and low HDL2C levels were found in both men and women. Apolipoprotein A and B followed the trends of HDLC and LDLC and showed no difference between the sexes. The plasma triglyceride (TG) levels increased with age in both sexes. Men displayed higher TG levels than women in all age groups. Seventeen per cent of men and 26% of women had a moderate-to-high risk for CHD, given their TC levels. Other lipid-related risk factors indicated low risk for CHD.

摘要

目的

确定开普半岛城市南非黑人人口的血脂和脂蛋白谱。

设计

横断面设计。

地点

开普半岛的七个黑人居住区。

参与者

从研究区域抽取分层比例样本。样本包括422名男性和544名年龄在15至64岁之间的女性。

观察指标

血脂和脂蛋白水平。冠心病(CHD)风险水平。

结果

与其他研究的南非群体相比,总胆固醇(TC水平)较低。男性的平均TC为3.98 mmol/l,女性为4.15 mmol/l。男性的低密度脂蛋白胆固醇(LDLC)值(2.03 mmol/l)低于女性(2.30 mmol/l)。男性(1.35 mmol/l)和女性(1.37 mmol/l)的高密度脂蛋白胆固醇(HDLC)水平相似。所有年龄组中,男女两性的保护性HDL/TC比值患病率均高于30%。男性和女性均发现HDL3C水平高而HDL2C水平低。载脂蛋白A和B遵循HDLC和LDLC的趋势,且两性之间无差异。血浆甘油三酯(TG)水平在男女两性中均随年龄增加。在所有年龄组中,男性的TG水平均高于女性。根据他们的TC水平,17%的男性和26%的女性有中度至高度的冠心病风险。其他与脂质相关的风险因素表明冠心病风险较低。

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