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选择性颈动脉内膜切除术前行脑部计算机断层扫描的批判性分析及其与颈动脉狭窄的相关性。

A critical analysis of cerebral computed tomography scanning before elective carotid endarterectomy and its correlation to carotid stenosis.

作者信息

AbuRahma A F, Robinson P A, Killmer S M, Kioschos J M, Roberts M D

机构信息

Department of Surgery, Robert C. Byrd Health Sciences Center of West Virginia University, Charleston, USA.

出版信息

Surgery. 1996 Mar;119(3):248-51. doi: 10.1016/s0039-6060(96)80109-7.

Abstract

BACKGROUND

Cerebral computed tomography (CT) scanning has been suggested to play a role in the management of patients before carotid endarterectomy (CEA). This prospective study analyzes the value of CT scanning before elective CEA and the correlation of CT findings to significant carotid stenosis.

METHODS

This study includes 131 consecutive patients considered for CEA during a 2-year period. All patients underwent carotid duplex ultrasonography, carotid arteriography, and CT scanning.

RESULTS

Eighty patients (61%) had transient ischemic attacks or prior strokes, and 51 (39%) had nonhemispheric symptoms or were asymptomatic. The CT scan was abnormal in 36 (27%) patients; however, no brain tumors or abnormalities to affect clinical management were revealed. Ninety-two CEAs were performed on 87 patients. Twenty-nine (32%) in the operative group had abnormal CT scans, but these did not influence operative decisions. On the basis of this rate of 0% of patients with CT findings to change surgical management in 92 cases, a maximum true rate of occurrence of up to 5% could be detected with alpha equals 0.05 by sampling a population of this size. Four patients (4%) had postoperative cerebral vascular accidents, and all of these had normal preoperative scans. Patients with 50% or more carotid stenosis on arteriogram were significantly more likely to have abnormal CT scans than patients with less than 50% stenosis (20% versus 7%, p = 0.0034). As carotid stenosis became more significant, the frequency of abnormal CT scans increased (p < 0.01). The cost of CT scanning was $66,089.50 in this study.

CONCLUSIONS

Significant carotid stenosis was associated with a higher frequency of abnormal CT scans; however, routine preoperative CT scanning was unnecessary before elective CEA.

摘要

背景

有人提出脑计算机断层扫描(CT)在颈动脉内膜切除术(CEA)前对患者的管理中发挥作用。这项前瞻性研究分析了择期CEA前CT扫描的价值以及CT结果与显著颈动脉狭窄的相关性。

方法

本研究纳入了在两年期间考虑进行CEA的131例连续患者。所有患者均接受了颈动脉双功超声检查、颈动脉血管造影和CT扫描。

结果

80例患者(61%)有短暂性脑缺血发作或既往中风史,51例(39%)有非半球性症状或无症状。36例(27%)患者的CT扫描异常;然而,未发现影响临床管理的脑肿瘤或异常情况。对87例患者进行了92次CEA手术。手术组中有29例(32%)患者的CT扫描异常,但这些并未影响手术决策。基于92例患者中CT检查结果改变手术管理的发生率为0%,通过对该规模人群进行抽样,在α等于0.05的情况下,最多可检测到高达5%的真实发生率。4例患者(4%)术后发生脑血管意外,所有这些患者术前扫描均正常。血管造影显示颈动脉狭窄50%或以上的患者比狭窄小于50%的患者CT扫描异常的可能性显著更高(分别为20%和7%,p = 0.0034)。随着颈动脉狭窄程度加重,CT扫描异常的频率增加(p < 0.01)。本研究中CT扫描的费用为66,089.50美元。

结论

显著的颈动脉狭窄与CT扫描异常的频率较高相关;然而,择期CEA前常规术前CT扫描并无必要。

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