Yamanaka A, Hirai K, Kato T, Naito Y, Takazoe I, Okuda K, Okuda K
Department of Microbiology, Tokyo Dental College, Japan.
Bull Tokyo Dent Coll. 1993 Nov;34(4):167-71.
Sterilization and disinfection in dental clinics and laboratories are important in controlling disease vectors such as methicillin-resistant Staphylococcus aureus (MRSA) and human immunodeficiency virus (HIV). We determined the inactivation of disinfectant effects of "Taisalite" and "Taifresh Ace" containing Irgasan DP300 on MRSA, Streptococcus pyogenes, Candida albicans, and HIV. Exposure for 10 seconds to 50% or 5% Taisalite solution inactivated HIV completely. HIV was also completely inactivated by 10 minutes of exposure to 50% or 5% of Taifresh Ace solution. Taisalite possessed strong bactericidal activity against S. pyogenes and MRSA. C. albicans was resistant to 10 to 30 second exposures to Taisalite. MRSA and C. albicans were killed completely by exposure to 90% Taifresh Ace solution for 10 minutes. S. pyogenes was not highly sensitive to Taifresh Ace. The present study showed that Irgasan DP300 containing Taisalite is an excellent disinfectant against HIV and MRSA and that Taifresh Ace is a useful detergent against these micro-organisms.
牙科诊所和实验室的消毒灭菌对于控制诸如耐甲氧西林金黄色葡萄球菌（MRSA）和人类免疫缺陷病毒（HIV）等疾病传播媒介至关重要。我们测定了含有三氯生的“太沙利特”和“太新鲜王牌”对MRSA、化脓性链球菌、白色念珠菌和HIV的消毒效果灭活情况。将HIV暴露于50%或5%的太沙利特溶液中10秒可使其完全灭活。将HIV暴露于50%或5%的太新鲜王牌溶液中10分钟也可使其完全灭活。太沙利特对化脓性链球菌和MRSA具有很强的杀菌活性。白色念珠菌对暴露于太沙利特10至30秒具有抗性。将MRSA和白色念珠菌暴露于90%的太新鲜王牌溶液中10分钟可将其完全杀灭。化脓性链球菌对太新鲜王牌不太敏感。本研究表明，含有三氯生的太沙利特是一种针对HIV和MRSA的优秀消毒剂，而太新鲜王牌是一种针对这些微生物的有用清洁剂。
