血小板活化因子，大鼠过敏反应中止血改变的触发因素。
Platelet activating factor, the trigger of haemostatic alterations in rat anaphylaxis.
作者信息
Fésüs L, Csaba B, Muszbek L
出版信息
Clin Exp Immunol. 1977 Mar;27(3):512-5.
Abstract
Platelet-activating factor (PAF) generated by an IgE-mediated reaction in the peritoneal cabity of rats was partially purified by adsorption to diatomaceous earth. It aggregated rat platelets and, as a consequence, activated Hageman factor in in vitro, as well as in vivo, conditions. The haemostatic alterations induced by PAF showed similarity to those observed in the early phase of rat anaphylaxis.
摘要
通过吸附到硅藻土上对大鼠腹膜腔内由IgE介导的反应产生的血小板活化因子（PAF）进行了部分纯化。它能使大鼠血小板聚集，结果在体外以及体内条件下激活了哈格曼因子。PAF诱导的止血改变与在大鼠过敏反应早期观察到的改变相似。
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本文引用的文献
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Aggregation of blood platelets by adenosine diphosphate and its reversal.二磷酸腺苷引起的血小板聚集及其逆转
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Platelet count by phase contrast microscopy--new diluting fluid for better visualization.相差显微镜法检测血小板计数——用于更好观察效果的新型稀释液
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Platelet-activating factor, a new mediator of anaphylaxis and immune complex deposition from rabbit and human basophils.血小板活化因子，一种来自兔和人嗜碱性粒细胞的过敏反应及免疫复合物沉积的新介质。
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Reduced aggregability of platelets in rat anaphylaxis.
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Measurement of fibrinolysis in rat system by one-dimensional diffusion method.采用一维扩散法测定大鼠系统中的纤维蛋白溶解情况。
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Activation and consumption of Hageman factor in the anaphylactic shock of the rat.大鼠过敏性休克中哈格曼因子的激活与消耗
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