Lewis D F, Futayyeh S, Towers C V, Asrat T, Edwards M S, Brooks G G
Department of Obstetrics and Gynecology, Louisiana State University Medical Center, Shreveport 71130, USA.
Am J Obstet Gynecol. 1996 Feb;174(2):525-8. doi: 10.1016/s0002-9378(96)70421-0.
Our purpose was to evaluate the necessity of using tocolytic agents for preterm labor and the benefit of conservative management for preterm premature rupture of membranes from 34 to 37 weeks' gestation. All patients who had accurate obstetric dates and were delivered between 34 and 37 weeks' gestation with no other medical or obstetric problems were retrospectively evaluated for inclusion in the study. The rates of respiratory distress syndrome and other neonatal outcomes were evaluated. A total of 416 patients met criteria for admission into the study. During the thirty-fourth week of pregnancy the incidence of respiratory distress syndrome was 14.9% (p<0.05). Other neonatal complications were also more frequent in deliveries occurring during the thirty-fourth week of pregnancy than in those occurring in the thirty-fifth or thirty-sixth week. Fetal lung maturity studies should be considered and delivery possibly delayed through the thirty-fourth week of gestation to decrease neonatal morbidity in our population.
我们的目的是评估在妊娠34至37周时，使用宫缩抑制剂治疗早产的必要性以及对胎膜早破进行保守治疗的益处。对所有产科日期准确、在妊娠34至37周分娩且无其他内科或产科问题的患者进行回顾性评估，以确定是否纳入研究。评估呼吸窘迫综合征及其他新生儿结局的发生率。共有416例患者符合纳入该研究的标准。在妊娠第34周时，呼吸窘迫综合征的发生率为14.9%（p<0.05）。与在妊娠第35或36周分娩的情况相比，妊娠第34周分娩时其他新生儿并发症也更常见。应考虑进行胎儿肺成熟度检查，并可能将分娩推迟至妊娠第34周，以降低我们研究人群中的新生儿发病率。
