药物的碳-13磁共振波谱分析II：抗组胺药
Carbon-13 magnetic resonance spectroscopy of drugs II: antihistamines.
作者信息
Chang C J, Peck G E
出版信息
J Pharm Sci. 1976 Jul;65(7):1019-23. doi: 10.1002/jps.2600650716.
PMID:8624
Abstract
The natural abundance carbon-13 magnetic resonance spectra of a series of antihistamines (pheniramine, chlorpheniramine, methapyrilene, tripelennamine, pyrilamine, and thonzylamine) were detemined using the pulse Fourier transform technique. The chemical shifts were assigned with the aid of long-range carbon-13-hydrogen coupling constants.
摘要
采用脉冲傅里叶变换技术测定了一系列抗组胺药（非尼拉敏、氯苯那敏、美吡拉敏、曲吡那敏、吡苄明和托恩西胺）的天然丰度碳-13磁共振谱。借助远程碳-13-氢耦合常数确定了化学位移。
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