Greenstein G
Department of Periodontology, University of Medicine and Dentistry, Newark, New Jersey, USA.
Compend Contin Educ Dent. 1995 May;16(5):448-55; quiz 456.
This article addresses the use of tetracycline-impregnated fibers in the treatment of periodontal diseases. Clinical and microbiologic data are reviewed to provide pragmatic guidelines for fiber use. In addition, controversial issues associated with the labeling of Actisite, the potential of developing antibiotic-resistant strains, and the benefits of systemic vs local drug delivery are discussed. Ultimately, the article concludes that tetracycline-impregnated fibers can be used as an adjunct to scaling and root planing in certain patients at sites that do not respond to conventional therapy.
本文探讨了四环素浸渍纤维在牙周疾病治疗中的应用。回顾了临床和微生物学数据，以提供纤维使用的实用指南。此外，还讨论了与Actisite标签相关的争议问题、产生抗生素耐药菌株的可能性以及全身给药与局部给药的益处。最终，本文得出结论，四环素浸渍纤维可作为常规治疗无效部位的某些患者进行龈下刮治和根面平整的辅助治疗手段。
