Cattabriga M, Pedrazzoli V, Cattabriga A, Pannuti E, Trapani M, Verrocchi G C
Department of Periodontology, University of Rome, La Sapienza, Italy.
Quintessence Int. 1996 Jun;27(6):395-400.
This study evaluated the 6-month clinical response to sustained-release tetracycline fibers used alone or with scaling and root planing in 25 adult periodontal maintenance patients. All subjects had at least one pocket > or = 4.0 mm that bled on probing and required therapy. Thirty-six teeth were treated with tetracycline fibers for 7 to 12 days; twelve of the 36 teeth also received scaling and root planing. The selection of teeth for scaling and root planing was based on the condition of the teeth. Therapeutic results were evaluated by changes in probing depth and frequency of bleeding on probing. Use of tetracycline fibers and fibers with scaling produced 1.8- and 1.7-mm reductions in probing depth, respectively, 1 month after treatment; reductions declined to 1.3 and 0.8 mm at 3 months, but rebounded to 1.5 and 1.3 mm at 6 months. The percentage of teeth exhibiting bleeding on probing decreased from 100% at baseline to 68% and 50% in the fiber and fiber plus scaling groups, respectively, at 6 months. None of the differences was statistically significant. Tetracycline fibers clearly decreased clinical signs of periodontal inflammation. Addition of scaling and root planing at the time of fiber placement further decreased, although not significantly, the degree of inflammation.
本研究评估了25名成人牙周维护患者单独使用缓释四环素纤维或联合龈下刮治和根面平整术治疗6个月后的临床反应。所有受试者至少有一个探诊深度≥4.0 mm且探诊出血并需要治疗的牙周袋。36颗牙齿用四环素纤维治疗7至12天；这36颗牙齿中的12颗还接受了龈下刮治和根面平整术。龈下刮治和根面平整术的牙齿选择基于牙齿状况。通过探诊深度的变化和探诊出血频率评估治疗效果。治疗1个月后，使用四环素纤维和联合龈下刮治的纤维分别使探诊深度降低了1.8 mm和1.7 mm；3个月时降低至1.3 mm和0.8 mm，但6个月时反弹至1.5 mm和1.3 mm。探诊出血的牙齿百分比在6个月时从基线时的100%分别降至纤维组的68%和纤维联合龈下刮治组的50%。所有差异均无统计学意义。四环素纤维明显减轻了牙周炎症的临床症状。在放置纤维时联合龈下刮治和根面平整术进一步减轻了炎症程度，尽管不显著。
