Jones W B, Schneider J, Shapiro F, Lewis J L
Gynecology Service Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.
Gynecol Oncol. 1996 Apr;61(1):126-30. doi: 10.1006/gyno.1996.0110.
Two patients with resistant gestational choriocarcinoma were treated w with Taxol after extensive prior chemotherapy including EMACO and platinum-based salvage chemotherapy. Both patients showed significant responses to Taxol. One patient relapsed in the brain and liver after treatment and died. Taxol was combined with carboplatin in the other patient who achieved sustained clinical and hormonal remission after craniotomy and excision of resistant disease in the brain.