Fang J, Keh P, Katz L, Rao M S
Department of Pathology, Northwestern University Medical School, Chicago, Illinois 60611, USA.
Gynecol Oncol. 1996 May;61(2):291-3. doi: 10.1006/gyno.1996.0142.
A case of high-grade endometrioid adenosquamous carcinoma of the ovary showing pilomatricoma-like areas and neuroendocrine differentiation is presented. The pilomatricoma-like areas were strongly positive for cytokeratin and vimentin, whereas the poorly differentiated areas of the tumor were positive for cytokeratin, synaptophysin, and neuron-specific enolase. Review of the literature did not show any published report of adenosquamous carcinoma with pilomatricoma-like areas either in the ovary or in the uterus.
本文报告一例卵巢高级别子宫内膜样腺鳞癌,其具有毛母质瘤样区域并伴有神经内分泌分化。毛母质瘤样区域细胞角蛋白和波形蛋白呈强阳性,而肿瘤的低分化区域细胞角蛋白、突触素和神经元特异性烯醇化酶呈阳性。文献回顾未发现卵巢或子宫中伴有毛母质瘤样区域的腺鳞癌的任何已发表报告。