饥饿期间mutT细菌的突变率升高：DNA周转的证据？
Elevated mutation rate in mutT bacteria during starvation: evidence for DNA turnover?
作者信息
Bridges B A
机构信息
MRC Cell Mutation Unit, University of Sussex, Brighton, Great Britain.
出版信息
J Bacteriol. 1996 May;178(9):2709-11. doi: 10.1128/jb.178.9.2709-2711.1996.
Abstract
The rate of appearance of prototrophic revertants when Escherichia coli tyrA14 (ochre) or trpA23 bacteria were incubated on plates lacking the required amino acid was greatly elevated when the organisms also carried a mutT mutation. One possible explanation for this result is that the amount of DNA replication or turnover under these conditions is much greater than has been previously recognized.
摘要
当大肠杆菌tyrA14（赭石型）或trpA23细菌在缺乏所需氨基酸的平板上培养时，如果这些生物体还携带mutT突变，原养型回复突变体的出现率会大大提高。这一结果的一种可能解释是，在这些条件下DNA复制或周转的量比之前认为的要大得多。
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