Matthews L A, Doershuk C F, Stern R C, Resnick M I
Department of Urology, University Hospitals of Cleveland, Ohio 44106-5046, USA.
J Urol. 1996 May;155(5):1563-4.
We determined whether cystic fibrosis patients are at increased risk for the development of urolithiasis.
Telephone interviews were conducted with 201 cystic fibrosis patients older than 15 years to identify those with a history of urolithiasis. Histories were confirmed by chart review, and only patients with urolithiasis documented by excretory urography, renal ultrasound or spontaneous passage of a stone were included.
A total of 11 patients (5.5%) had documented urolithiasis, with 2 or more episodes in 7. Mean age at initial episode was 27.0 years (range 19 to 33).
Cystic fibrosis patients may be at increased risk for urolithiasis compared to age-specific prevalence rates for stone disease in the general population.
我们确定囊性纤维化患者发生尿路结石的风险是否增加。
对201名15岁以上的囊性纤维化患者进行电话访谈，以确定有尿路结石病史的患者。通过查阅病历确认病史，仅纳入经排泄性尿路造影、肾脏超声检查证实有尿路结石或结石自行排出的患者。
共有11名患者（5.5%）有记录在案的尿路结石，其中7名患者有2次或更多发作。首次发作的平均年龄为27.0岁（范围19至33岁）。
与一般人群中按年龄划分的结石病患病率相比，囊性纤维化患者发生尿路结石的风险可能增加。
