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法洛四联症经皮右心室流出道球囊扩张术的姑息治疗

Palliative treatment for tetralogy of Fallot with percutaneous balloon dilatation of right ventricular outflow tract.

作者信息

Hwang B, Lu J H, Lee B C, Hsieng J H, Meng C C

机构信息

Department of Pediatrics, Veterans General Hospital-Taipei, Taiwan, ROC.

出版信息

Jpn Heart J. 1995 Nov;36(6):751-61. doi: 10.1536/ihj.36.751.

Abstract

Percutaneous balloon pulmonary dilatation of the right ventricular tract was performed on 16 children with tetralogy of Fallot for palliative purposes after routine cardiac catheterization. Immediate improvement in aortic saturation from 73.4 +/- 6.8 to 84.0 +/- 4.8% (mean +/- SD = 10.6 +/- 2.7%, p < 0.001) and clinical symptoms were achieved in all 16 cases. The pressures in the right ventricle, pulmonary artery, left ventricle and aorta showed no remarkable changes after percutaneous balloon dilatation. The diameters of the proximal end and at the first branching of the right and left pulmonary arteries, pulmonary arterial index and the diameter of the descending aorta at the diaphragm increased significantly after balloon dilatation (p value 0.0004-0.006). One child suffered from repeated cyanotic spells in spite of the immediate improvement of aortic saturation. She received a left side Blalock-Taussig shunt 2 months after the balloon dilatation. None of the children had a significant complication. Eight had follow-up cardiac catheterization one year later and demonstrated much improvement in the diameters of the proximal end and at the first branching of the right and left pulmonary arteries, pulmonary arterial index and the diameter of the descending aorta at the diaphragm (p value 0.005-0.04). All 8 patients had their cardiac lesions successfully corrected. Percutaneous balloon dilatation is an alternative palliative therapy for children with tetralogy of Fallot.

摘要

在16例法洛四联症患儿中,于常规心导管检查后,为姑息治疗目的进行了经皮球囊肺动脉瓣扩张术。所有16例患儿的主动脉血氧饱和度立即从73.4±6.8%提高到84.0±4.8%(平均±标准差 = 10.6±2.7%,p<0.001),临床症状也得到改善。经皮球囊扩张术后,右心室、肺动脉、左心室和主动脉的压力无明显变化。球囊扩张术后,左右肺动脉近端及第一分支处的直径、肺动脉指数及膈肌水平降主动脉直径均显著增加(p值0.0004 - 0.006)。尽管主动脉血氧饱和度立即得到改善,但仍有1例患儿出现反复青紫发作。球囊扩张术后2个月,她接受了左侧Blalock-Taussig分流术。所有患儿均无严重并发症。8例患儿在1年后接受了随访心导管检查,结果显示左右肺动脉近端及第一分支处的直径、肺动脉指数及膈肌水平降主动脉直径均有明显改善(p值0.005 - 0.04)。所有8例患者的心脏病变均成功矫正。经皮球囊扩张术是法洛四联症患儿的一种替代性姑息治疗方法。

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