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[法洛四联症肺动脉道的经皮扩张术]

[Percutaneous dilatation of the pulmonary tract in tetralogy of Fallot].

作者信息

Guérin P, Jimenez M, Dos Santos P, Srour S, Choussat A

机构信息

Service de cardiologie pédiatrique, hôpital cardiologique du Haut-Lévêque, Université de Bordeaux II, Pessac.

出版信息

Arch Mal Coeur Vaiss. 1996 May;89(5):541-5.

PMID:8758561
Abstract

When palliative treatment is indicated in tetralogy of Fallot, percutaneous endoluminal dilatation of the valvular pulmonary stenosis may represent an alternative to palliative surgery (systemico-pulmonary shunt) and its disadvantages. This paper sets out the clinical outcome and growth of the pulmonary arterial circulation after dilatation of the valvular pulmonary stenosis in children with tetralogy of Fallot. Twenty-five children (average age: 8 +/- 5.8 week; average weight: 6.7 +/- 2.4 kg) were included in this study. The dilatation resulted in an immediate decrease in the patients' cyanosis and a significant increase (+10%) in arterial oxygen saturation. However, this technique did not suppress the risk of anoxic malaise. Only 5 children (20%) required a palliative surgical shunt for persistence of anoxic malaise. From the anatomical point of view, the dilatation induced significant growth of the pulmonary annulus (7.6 mm vs 11.3 mm; p < 0.0001), of the main pulmonary artery (6.8 mm vs 10 mm); p = 0.008) and left pulmonary artery (7 mm vs 11 mm; p = 0.02). The need for a procedure to widen the right ventricular outflow tract at the time of complete correction was also reduced. The perioperative mortality of complete correction and postoperative pulmonary insufficiency were decreased. Percutaneous dilatation of the right ventricular outflow tract is therefore a valuable palliative alternative to surgical sytemico-pulmonary shunt.

摘要

当法洛四联症需要姑息治疗时,经皮腔内瓣膜肺动脉狭窄扩张术可能是姑息性手术(体肺分流术)及其缺点的一种替代方法。本文阐述了法洛四联症患儿瓣膜肺动脉狭窄扩张术后的临床结果及肺动脉循环的生长情况。本研究纳入了25名儿童(平均年龄:8±5.8周;平均体重:6.7±2.4千克)。扩张术使患者的发绀立即减轻,动脉血氧饱和度显著升高(升高10%)。然而,该技术并未消除缺氧不适的风险。只有5名儿童(20%)因缺氧不适持续存在而需要进行姑息性手术分流。从解剖学角度来看,扩张术使肺动脉瓣环显著增大(从7.6毫米增至11.3毫米;p<0.0001),主肺动脉增大(从6.8毫米增至10毫米;p=0.008),左肺动脉增大(从7毫米增至11毫米;p=0.02)。在完全矫正时扩大右心室流出道的手术需求也减少了。完全矫正的围手术期死亡率和术后肺功能不全有所降低。因此,经皮右心室流出道扩张术是手术体肺分流术的一种有价值的姑息替代方法。

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