Daida H, Allison T G, Squires R W, Miller T D, Gau G T
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic Rochester, Minnesota 55905, USA.
Mayo Clin Proc. 1996 May;71(5):445-52. doi: 10.4065/71.5.445.
To determine the peak blood pressure responses during symptom-limited exercise in a large sample of apparently healthy subjects, including both men and women over a wide range of ages.
We retrospectively studied the blood pressure response during maximal treadmill exercise testing with use of the Bruce protocol in apparently healthy subjects.
Peak exercise blood pressures in 7,863 male and 2,406 female apparently healthy subjects who underwent a screening treadmill exercise test with the Bruce protocol between 1988 and 1992 were analyzed by age and gender.
In this large referral population of apparently healthy subjects, peak exercise systolic and diastolic blood pressures and delta systolic blood pressure (rest to peak exercise) were higher in men than in women and were positively associated with age. In men, the 90th percentile of systolic blood pressure increased from 210 mm Hg for the age decade 20 to 29 years to 234 mm Hg for ages 70 to 79 years; the corresponding increase among women was from 180 mm Hg to 220 mm Hg. Delta diastolic blood pressure also increased with advancing age. The difference in peak and delta systolic blood pressures between men and women seemed to decrease after age 40 to 49 years. Exercise hypotension, defined as peak exercise systolic pressure less than rest systolic pressure, occurred in 0.23% of men and 1.45% of women and was not significantly related to age.
Overall, peak exercise systolic and diastolic, as well as delta systolic, blood pressures were higher in men than in women and increased with advancing age. The reported data will enable clinicians to interpret more accurately the significance of peak exercise blood pressure response in a subject of a specific age and gender and will allow investigators to define exercise hypertension in statistical terms stratified by age and gender.
在大量看似健康的受试者样本中，确定症状限制运动期间的血压峰值反应，这些受试者包括不同年龄段的男性和女性。
我们回顾性研究了使用布鲁斯方案对看似健康的受试者进行最大运动平板试验时的血压反应。
对1988年至1992年间使用布鲁斯方案进行筛选运动平板试验的7863名男性和2406名女性看似健康的受试者的运动血压峰值，按年龄和性别进行分析。
在这个大量看似健康的转诊人群中，男性运动收缩压、舒张压峰值以及收缩压差值（静息至运动峰值）均高于女性，且与年龄呈正相关。在男性中，收缩压第90百分位数从20至29岁年龄段的210 mmHg增加到70至79岁年龄段的234 mmHg；女性相应的增加幅度为从180 mmHg至220 mmHg。舒张压差值也随年龄增长而增加。40至49岁之后，男性和女性在收缩压峰值和差值方面的差异似乎减小。运动性低血压定义为运动收缩压峰值低于静息收缩压，在0.23%的男性和1.45%的女性中出现，且与年龄无显著相关性。
总体而言，男性运动收缩压、舒张压以及收缩压差值峰值均高于女性，并随年龄增长而升高。所报告的数据将使临床医生能够更准确地解释特定年龄和性别的受试者运动血压峰值反应的意义，并使研究人员能够按年龄和性别分层从统计学角度定义运动性高血压。
