甲状腺乳头状许特莱细胞肿瘤：一例经细胞形态学方法诊断的病例报告。
Papillary Hürthle cell tumor of thyroid: report of a case with a cytomorphologic approach to diagnosis.
作者信息
Dziecioł J, Musiatowicz B, Zimnoch L, Kemona A, Sulkowski S
机构信息
Department of Pathological Anatomy, Białystok, Poland.
出版信息
Acta Cytol. 1996 Mar-Apr;40(2):311-4. doi: 10.1159/000333758.
BACKGROUND
Hürthle cells are founded often in fine needle aspirates of the thyroid from nonneoplastic and neoplastic lesions. Papillary Hürthle cell tumors of the thyroid are composed of oxyphilic cells with a prominent papillary component. Papillary Hürthle cell carcinoma is a relatively uncommon type of thyroid carcinoma.
CASE
A 42-year-old man had two asymptomatic nodules (2.5 and 3.5 cm) in the left lobe and one (2.5 cm) in the right lobe of the thyroid. Fine needle aspiration biopsy of the tumor in the left lobe showed large cells in monolayers and papillary clusters with moderate to abundant eosinophilic, granular cytoplasm with sharp borders, a granular nuclear enlargement with pleomorphism and single nucleoli. Histologic examination showed capsular invasion and infiltration of vessels.
CONCLUSION
The cytologic appearance of papillary Hürthle cell carcinoma is not specific but can be suspected on fine needle aspiration.
背景
在甲状腺非肿瘤性和肿瘤性病变的细针穿刺抽吸物中常发现许特莱细胞。甲状腺乳头状许特莱细胞瘤由具有显著乳头成分的嗜酸性细胞组成。乳头状许特莱细胞癌是一种相对罕见的甲状腺癌类型。
病例
一名42岁男性，甲状腺左叶有两个无症状结节（2.5厘米和3.5厘米），右叶有一个（2.5厘米）。左叶肿瘤的细针穿刺活检显示单层大细胞和乳头状细胞簇，伴有中度至丰富的嗜酸性、颗粒状细胞质，边界清晰，核颗粒状增大，有异形性和单个核仁。组织学检查显示有包膜侵犯和血管浸润。
结论
乳头状许特莱细胞癌的细胞学表现不具有特异性，但在细针穿刺时可怀疑该病。
Zotero 插件