重组α-2b干扰素治疗慢性丙型肝炎后发生的心源性休克。一例病例报告。

Cardiogenic shock following recombinant alpha-2b interferon therapy for chronic hepatitis C. A case report.

作者信息

Teragawa H, Hondo T, Amano H, Watanabe H, Ohe H, Hattori N, Watanabe Y, Hino F, Ohbayashi M

机构信息

Department of Internal Medicine, Onomichi General Hospital, Hiroshima, Japan.

出版信息

Jpn Heart J. 1996 Jan;37(1):137-42. doi: 10.1536/ihj.37.137.

DOI:10.1536/ihj.37.137

PMID:8632622

Abstract

A 57-year-old woman with chronic hepatitis C was treated with alpha-2b interferon (IFN). Forty-five days after the initiation of IFN therapy, she developed cardiogenic shock. Acute perimyocarditis as a cause of cardiogenic shock was clinically suspected by the findings of complete atrioventricular block, regional wall motion abnormality and pericardial effusion. Since IFN therapy may induce cardiogenic shock in some patients, it is important to carefully monitor patients under treatment with IFN for abnormal cardiac signs.

摘要

一名57岁的慢性丙型肝炎女性患者接受了α-2b干扰素（IFN）治疗。IFN治疗开始45天后，她出现了心源性休克。根据完全性房室传导阻滞、局部室壁运动异常和心包积液的表现，临床上怀疑急性心包心肌炎是心源性休克的病因。由于IFN治疗可能会在一些患者中诱发心源性休克，因此在IFN治疗期间仔细监测患者的心脏异常体征非常重要。