Amyloidosis and silicone synovitis: updated classification, updated pathophysiology, and synovial articular abnormalities.

Amyloidosis is a heterogeneous group of disorders characterized by the extracellular deposition of protein fibrils in organs or tissues. Silicone synovitis, like amyloid arthropathy, is characterized radiographically by multiple subchondral cysts in the absence of cartilage space narrowing. This article examines and compares the classification, pathophysiology, and synovial articular abnormalities associated with amyloidosis and silicone synovitis.