Hansell D M, Wells A U, Padley S P, Müller N L
Department of Radiology, Royal Brompton Hospital, London, England.
Radiology. 1996 Apr;199(1):123-8. doi: 10.1148/radiology.199.1.8633133.
To correlate the pattern and extent of abnormalities on thin-section computed tomographic (CT) scans with pulmonary function test results in subacute and chronic hypersensitivity pneumonitis.
Thin-section scans (1-3 mm collimation) obtained in 22 patients were assessed for pattern of abnormality and extent of disease. CT scores were correlated with functional parameters by using Spearman rank correlation and forward stepwise regression analysis.
The most common CT patterns were decreased attenuation and mosaic perfusion (n = 19), ground-glass opacification (n = 18), small nodules (n = 12), and a reticular pattern (n = 8). Areas of decreased attenuation correlated with severity of air trapping indicated by residual volume (r = .58, P < .01), whereas ground-glass opacification and reticulation correlated independently with restrictive lung function.
Areas of decreased attenuation and mosaic perfusion are an important ancillary CT finding in hypersensitivity pneumonitis, and obstructive functional abnormalities indicate that this phenomenon is caused by bronchiolitis.
将亚急性和慢性过敏性肺炎患者薄层计算机断层扫描（CT）的异常模式及范围与肺功能测试结果进行关联。
对22例患者的薄层扫描（准直1 - 3毫米）进行异常模式及疾病范围评估。通过Spearman等级相关分析和向前逐步回归分析将CT评分与功能参数进行关联。
最常见的CT模式为密度减低和马赛克灌注（n = 19）、磨玻璃样混浊（n = 18）、小结节（n = 12）及网状模式（n = 8）。密度减低区域与残气量所提示的气体陷闭严重程度相关（r = 0.58，P < 0.01），而磨玻璃样混浊和网状模式与限制性肺功能独立相关。
密度减低区域和马赛克灌注是过敏性肺炎重要的CT辅助表现，阻塞性功能异常提示该现象由细支气管炎所致。
