冠状动脉搭桥术后神经心理功能障碍的界定
Defining neuropsychological dysfunction after coronary artery bypass grafting.
作者信息
Mahanna E P, Blumenthal J A, White W D, Croughwell N D, Clancy C P, Smith L R, Newman M F
机构信息
Department of Psychiatry, Duke University Medical Center, Durham, North Carolina 22710, USA.
出版信息
Ann Thorac Surg. 1996 May;61(5):1342-7. doi: 10.1016/0003-4975(95)01095-5.
BACKGROUND
Despite the large body of literature documenting the presence of cognitive decline after coronary artery bypass grafting, there is little consensus as to the frequency and extent of cognitive impairment. One potential reason for this lack of agreement is the absence of uniform criteria for assessing cognitive decline.
METHODS
Two hundred thirty-two patients underwent cognitive testing the day before operation and were examined before discharge, and at 6 weeks and 6 months after grafting. For comparative purposes, five different sets of criteria were used to define cognitive decline.
RESULTS
There was little agreement between the criteria as to which patients declined at each test period. The incidence of decline ranged from 66% to 15.3% before discharge, 34% to 1.1% at 6 weeks, and 19.4% to 3.4% at 6 months.
CONCLUSIONS
A large variation in reported incidence of cognitive decline after coronary artery bypass grafting can be attributed to the different criteria used to define cognitive impairment.
背景
尽管有大量文献记载冠状动脉搭桥术后存在认知功能下降，但对于认知障碍的发生率和程度几乎没有共识。缺乏一致性的一个潜在原因是缺乏评估认知功能下降的统一标准。
方法
232例患者在手术前一天进行认知测试，并在出院前、移植后6周和6个月时接受检查。为了进行比较，使用了五套不同的标准来定义认知功能下降。
结果
在每个测试阶段，各标准对于哪些患者认知功能下降几乎没有一致性。出院前认知功能下降的发生率在66%至15.3%之间，6周时在34%至1.1%之间，6个月时在19.4%至3.4%之间。
结论
冠状动脉搭桥术后认知功能下降的报告发生率差异很大，这可归因于用于定义认知障碍的不同标准。
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