人成纤维细胞干扰素的稳定和不稳定形式。
Stable and unstable forms of human fibroblast interferon.
作者信息
Edy V G, Desmyter J, Billiau A, De Somer P
出版信息
Infect Immun. 1977 May;16(2):445-8. doi: 10.1128/iai.16.2.445-448.1977.
Abstract
There is a minor fraction of human fibroblast interferon that resembles human leukocyte interferon in being renaturable after treatment with guanidine hydrochloride. However, antigenically and in its low activity on heterologous cells, it resembles the bulk of human fibroblast interferon. Since the production of this stable interferon fraction is not greatly inhibited by glucosamine at concentrations that significantly reduce total interferon production, it is suggested that it differs from the bulk of human fibroblast interferon in the extent or nature of glycosylation.
摘要
有一小部分人成纤维细胞干扰素，在用盐酸胍处理后可复性，这一点与人类白细胞干扰素相似。然而，在抗原性及其对异源细胞的低活性方面，它与大部分人成纤维细胞干扰素相似。由于在显著降低总干扰素产量的浓度下，葡糖胺对这种稳定的干扰素组分的产生没有很大抑制作用，因此表明它在糖基化程度或性质上与大部分人成纤维细胞干扰素不同。
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Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
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Molecular structure of human fibroblast and leukocyte interferons: probe by lectin and hydrophobic chromatography.人成纤维细胞干扰素和白细胞干扰素的分子结构：通过凝集素和疏水色谱法进行探测
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