静脉注射牛血清的兔子出现类风湿样关节病变。
Rheumatoid-like joint lesions in rabbits injected intravenously with bovine serum.
作者信息
Poole A R, Coombs R R
出版信息
Int Arch Allergy Appl Immunol. 1977;54(2):97-113. doi: 10.1159/000231813.
PMID:863527
Abstract
Rheumatoid-like synovial lesions have been produced experimentally in 21% of rabbits receiving intravenous injections of bovine serum by various regimens. They were characterized by lining cell hyperplasia, accumulations, often follicular, of lymphocytes and plasma cells just under the lining layer, sometimes with extensive fibroplasia and pannus formation with cartilage erosion.
摘要
通过各种方案给兔子静脉注射牛血清后，21%的兔子实验性地产生了类风湿样滑膜病变。其特征为衬里细胞增生，衬里层下方常有淋巴细胞和浆细胞聚集，常呈滤泡状，有时伴有广泛的纤维增生和血管翳形成以及软骨侵蚀。
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