Bone R C
Medical College of Ohio, Toledo, USA.
Chest. 1996 Apr;109(4):1056-65. doi: 10.1378/chest.109.4.1056.
The past 15 years have seen a rise in mortality and morbidity resulting from asthma, despite a concurrent rise in general knowledge about the disease. The step-care strategy recognized these changes in its approach to asthma management; however, this approach should be used only with attempts to control environmental allergens. Step-care therapy requires that patients be categorized by the severity of illness. Step-one therapy is used for mild, infrequent symptoms and involves treatment based primarily on inhaled bronchodilators. Step-two therapy is instituted in all asthmatics except the mildest cases; it involves treatment by inhaled corticosteroids, cromolyn, or nedocromil. Step-three treatment targets cases of severe asthma through the use of oral corticosteroids. In all phases of treatment, however, it should be remembered that patient education is of critical importance. Education improves patient compliance and is critical to the successful treatment of asthma.
在过去的15年里,尽管人们对哮喘的一般认识有所提高,但因哮喘导致的死亡率和发病率却有所上升。阶梯式治疗策略在其哮喘管理方法中认识到了这些变化;然而,这种方法应仅在试图控制环境过敏原时使用。阶梯式治疗要求根据疾病的严重程度对患者进行分类。第一步治疗用于轻度、不频繁发作的症状,主要基于吸入性支气管扩张剂进行治疗。除最轻微的病例外,所有哮喘患者都采用第二步治疗;它包括使用吸入性皮质类固醇、色甘酸钠或奈多罗米进行治疗。第三步治疗通过使用口服皮质类固醇来针对严重哮喘病例。然而,在治疗的所有阶段都应记住,患者教育至关重要。教育可提高患者的依从性,对哮喘的成功治疗至关重要。