枯草芽孢杆菌谷氨酰胺合成酶基因操纵子的自体调控
Autogenous regulation of the Bacillus subtilis glnRA operon.
作者信息
Brown S W, Sonenshein A L
机构信息
Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts 02111, USA.
出版信息
J Bacteriol. 1996 Apr;178(8):2450-4. doi: 10.1128/jb.178.8.2450-2454.1996.
Abstract
Purified Bacillus subtilis GlnR was shown to bind with high affinity to a specific region that overlaps with the glnRA promoter site. The GlnR binding site includes four copies of a repeated sequence that may be the recognition site for the protein. GlnR inhibited transcription from the glnRA promoter in vitro.
摘要
纯化后的枯草芽孢杆菌GlnR被证明能以高亲和力与一个与glnRA启动子位点重叠的特定区域结合。GlnR结合位点包含一个重复序列的四个拷贝，该重复序列可能是该蛋白质的识别位点。GlnR在体外抑制了glnRA启动子的转录。
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